Triterpenoid constituents and Their Anti-cancer activity from stems and branches of Sambucus williamsii var. coreana Nakai (Caprifoliaceae)

نویسندگان

چکیده

This study aims at characterization of the anti-cancer active compounds separated from stems and branches Sambucus williamsii var. coreana Nakai (Caprifoliaceae). Bioactivity-guided fractionation ethanol extracts S. was isolated three triterpenoid compounds. fractions showed superior growth inhibitory activity against cancer cells (HCT116, A549 MDA-MB231). Active fraction analyzed led to identification using HPLC, NMR, LC-MS spectrometer, their structures were established as betulinic acid (1), oleanolic (2) ursolic (3). The results this performed with will be helpful develop new efficient agents. Also, research supported previous separations isolations studies on ingredients williamsii.

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ژورنال

عنوان ژورنال: Food Science and Technology

سال: 2021

ISSN: ['2331-513X', '2331-5156']

DOI: https://doi.org/10.1590/fst.76021